The main issue of the current research is that drugs affect public security and there is no doubt that people are the pillars of society. Therefore, whenever drugs dominate the society and the phenomenon of drug addiction appears in the society, the society will be sick with the most dangerous pests and stagnation, violation and backwardness will dominate the society and chaos will spread and that The society becomes an easy prey for the enemies to easily influence and dominate that society and their wealth, beliefs and religion and weaken them, and the weakening of the individual leads to the weakening of the efficiency of the society. Therefore, this process is a threat in general it is for production and national economy. The purpose of this research is to investigate and analyze the security and political aspects of drugs in the Middle East. For the statistical and graphical analysis of patterns of distribution centers of drug trafficking in the Middle East from statistical methods of average center Standard deviation ellipse and clustering tests including nearest neighbor and kernel density estimation method were used. The findings of the research show that during the years 2000 to 2021, the highest concentration of drug discovery is in Turkey, northern Syria, Iraq, Iran, Afghanistan, and Pakistan. That there are the most centers of crime in this area, that this area has a more critical situation than other regions in the Middle East. The countries of Qatar, the United Arab Emirates, and Kuwait have less density in terms of the distribution of drug crimes than other countries in the Middle East.